Cancer is recognized as a genetic disease. While gene expression generates a biological process, there is evidence that genes do not operate independently from each other in the process of gene expression and interconnected within a gene regulatory network. In this article, by introducing the tension factor into the gene expression regulation network of healthy and cancer cells, we will study how the two networks evolve and their differences from the point of view of structural balance. For this purpose, by using the structural balance dynamics in non-zero temperature and with the help of Boltzmann and equilibrium distribution function, we assign energy to each triangle at each specific temperature and measure the balance of the network. We observe that both networks are completely balanced at zero temperature. The balanced structure breaks down when the amount of tension increases at a characteristic temperature that is different for both networks; The cancer network exhibits a stronger resistance to destroying the balanced structure that it has created. Also, by examining the behavior of single genes, we understand the structural role of some of them; We observe that certain genes have a greater impact on the formation of balance in the network than others.
